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Human+AI, data, CRM and intelligent systems: what we learn building and operating, and the studies we publish.

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Research, Philosophy & Thought Leadership

AlphaFold to ISM8969: AI Reaches Its First Cancer Treatment

A pipeline review lands on your desk with three assets labelled AI-designed. One sits in Phase 1. One has just cleared IND-enabling studies. One is a slide with a colourful protein structure and no molecule attached. The label alone tells you nothing about which one deserves funding. The first AI-enabled cancer drugs are in clinical […]

5 May 2026 Read more →
Privacy By Design CRM Architecture: Architecture Patterns for Scale
Data Strategy & Analytics

Privacy By Design CRM Architecture: Architecture Patterns for Scale

Most CRM teams treat privacy as a legal checkbox. They bolt on consent banners after the fact, add a data deletion script when legal asks, and call it done. The cost of that approach compounds quietly until it doesn’t – a regulatory fine, a data breach disclosure, a customer churn spike that traces back to […]

5 May 2026 Read more →
ESP Vendor Lock-in Risks: What Changed and What Still Works
ESPs & Marketing Automation

ESP Vendor Lock-in Risks: What Changed and What Still Works

The companies losing the most money in email marketing are not the ones with bad creative. They are the ones trapped inside an ESP contract they signed three years ago, paying for features they cannot audit, running on shared infrastructure they do not control, with data they cannot easily extract. ESP vendor lock-in risks have […]

1 May 2026 Read more →
Best Open Source Email Marketing Platform: Buyer Checklist for Enterprise Teams
ESPs & Marketing Automation

Best Open Source Email Marketing Platform: Buyer Checklist for Enterprise Teams

Enterprise teams evaluating the best open source email marketing platform consistently underestimate one variable: total cost of ownership diverges sharply from licensing cost within 18 months. The platform is rarely the budget problem. The infrastructure around it is. Before you shortlist tools, run this checklist. What “Open Source” Actually Costs at Scale Open source eliminates […]

30 Apr 2026 Read more →
Predictive Customer Scoring Email: Architecture Patterns for Scale
CRM Optimization & Deliverability

Predictive Customer Scoring Email: Architecture Patterns for Scale

Most email scoring systems break at scale – not because the model is wrong, but because the architecture around it was never designed to handle production volume. Predictive customer scoring email is not a feature you bolt onto your ESP. It is a data pipeline with a model in the middle, and every component in […]

29 Apr 2026 Read more →
Email Deliverability Consultant: What Your Vendor Is Not Telling You
ESPs & Marketing Automation

Email Deliverability Consultant: What Your Vendor Is Not Telling You

Your ESP’s support team told you the emails were delivered. Your dashboard shows a 99% delivery rate. But revenue from email dropped 30% last quarter. These two facts are not contradictory – they are the exact gap an email deliverability consultant exists to explain. Delivery rate measures whether a server accepted your message. Inbox placement […]

28 Apr 2026 Read more →