In July 2021, DeepMind released the structures of around 350,000 proteins predicted by AlphaFold 2. By 2022, that database held over 200 million predicted structures, covering nearly every catalogued protein known to science. Structural biology had been working on this problem since the 1950s, and the experimental backlog at the Protein Data Bank stood at […]

Last quarter, a CRM manager at a mid-sized retailer asked me to review a propensity model her team was about to push into a reactivation campaign. The model worked. It identified lapsed customers most likely to convert with a 22% lift over the control. What it also did, when we looked closer, was systematically deprioritize […]

A CRM team I worked with last quarter ran the same lead scoring task two ways. In the first setup, an analyst used GPT-4 to draft segmentation logic, then approved it. In the second, the analyst and the model iterated together across six rounds, with the human reshaping prompts based on what each output revealed […]

Last quarter, a CRM manager I work with stopped opening her segmentation tool. She kept the tab pinned, but her actual workflow had moved into a chat window where an agent drafted SQL, ran the query against Snowflake, and returned a cohort with notes on data quality. She still made every decision about who got […]